Quinocin | 500 mg Tablet
Price: 12.000000
Indication
Quinocin is used in adults for the treatment of urinary tract infections, lower respiratory tract infections, skin and soft tissue infections, bone and joint infections and G.I. infections caused by susceptible gram-negative and gram-positive aerobic bacteria. It is also used for the treatment of uncomplicated gonorrhoea caused by penicillinase producing Neisseria gonorrhoeae.
Presentation
Quinocin 500: Each tablet contains Ciprofloxacin Hydrochloride USP equivalent to Ciprofloxacin 500 mg.
Dosages and Administration
Adults
The usual adult dose is between 500 mg-750 mg twice daily. In Respiratory infection the usual dose is 500 mg-750 mg twice daily. In infection of the bladder and kidneys, the usual dose is 250 mg-500 mg twice daily. In gonorrhoea, the usual dose is 250 mg-500 mg as a single dose. In gastro-intestinal infections, the usual dose is 500 mg twice daily. In intra-abdominal infections, skin and soft tissue infections, bone and joint infections and in neutropenic patients the usual dose is 500 mg-750 mg twice daily. In infections due to Bacterium Neisseria meningitidis the usual dose is 500 mg as a single dose. In case of inhalation anthrax exposure the usual dose is 500 mg twice daily.
Adult with creatinine clearance of 30-50 ml/minute can receive 250 mg-500 mg of Quinocin every 12 hours and adults with creatinine clearance of 5-29 ml/minute can receive 250 mg-500 mg every 18 hours.
Packaging
Quinocin 500: Box containing 3x10’s tablets in Alu-PVC blister pack.
Side Effects
Gastrointestinal disturbances e.g. nausea, diarrhoea, vomiting, dyspepsia, abdominal pain. Disturbances of the central nervous system e.g. headache, dizziness, tiredness, confusion, convulsion & risk of retinal detachment. Hypersensitivity reactions e.g. skin rash (very rarely Stevens-Johnson syndrome and toxic epidermal necrolysis), pruritus and possible systemic reactions. The other less reported reactions are joint pain, mild photosensitivity and transient increase in liver enzymes (particularly in patients with previous liver damage), serum bilirubin, urea or creatinine levels. Risk of hypoglycemia & mental health adverse effects.
Pregnancy
Reproduction studies performed in mice, rats and rabbits using parenteral and oral administration did not reveal any evidence of teratogenicity, impairment of fertility or impairment of peri/post natal development.
However as with other quinolones, Ciprofloxacin has been shown to cause arthropathy in immature animals and therefore its use during pregnancy is not recommended. Studies in rats have indicated that Ciprofloxacin is secreted in milk, administration to nursing mothers is thus not recommended.